- CAS Number:
- Sample Preparation:
- Contents:
- MSDS:
| 9087-70-1 | |
| Suggested Procedure | |
| Each vial contains 5ml of aprotinin.We recommend using 0.6 TIU of Aprotinin (100 µl) per 1 ml of blood. | |
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Aprotinin Stability Testing
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Whole-body cryostimulation as an effective method of reducing low-grade inflammation in obese men.
This study was aimed to evaluate anti-inflammatory effect of the whole body cryostimulation in obese men. Fourteen subjects (BMI >30 kg m(-2)), divided into two subgroups according to cardiorespiratory fitness: higher (HCF) or lower (LCF), have been exposed to 10 sessions in a cryogenic chamber (-110 °C). Blood samples were collected before, 30 min and 24 h after the first, fifth and last cryostimulation. Coldness exposures affected blood cytokine profile; however, the response depended on subjects" fitness capacity. Concentrations of pro-inflammatory cytokines in the LCF decreased by 19, 6.8, and 7.4 % in IL-6, resistin, and visfatin, respectively. TNFα in the LCF dropped 4.3-fold compared to baseline, while in the HCF, changes were smaller, yet significant. Anti-inflammatory cytokine IL-10 increased in both groups. No changes in adiponectin and leptin were observed in either group. Obtained results suggest that whole body cryostimulation can be a supplementary method for obese in reducing systemic inflammation.Ziemann E, Olek RA, Grzywacz T, et al. J Physiol Sci. 2013;63(5):333-43.
Aprotinin Inhibitory Activity on Trypsin
Whole-body cryostimulation as an effective method of reducing low-grade inflammation in obese men.Ziemann E, Olek RA, Grzywacz T, et al.J Physiol Sci. 2013;63(5):333-43.
Testosterone is a strong correlate of ghrelin levels in men and postmenopausal women.Greenman Y, Rouach V, Limor R, Gilad S, Stern N.Neuroendocrinology. 2009;89(1):79-85.
Effect of the glycemic index of carbohydrates on day-long (10 h) profiles of plasma glucose, insulin, cholecystokinin and ghrelin.Reynolds RC, Stockmann KS, Atkinson FS, Denyer GS, Brand-miller JC.Eur J Clin Nutr. 2009;63(7):872-8.
Circulating preprandial ghrelin to obestatin ratio is increased in human obesity.Guo ZF, Zheng X, Qin YW, Hu JQ, Chen SP, Zhang Z.J Clin Endocrinol Metab. 2007;92(5):1875-80.
C-type natriuretic peptide in individuals with normal left ventricular systolic function.Kuo JY, Yeh HI, Chang SH, et al.Scand Cardiovasc J. 2007;41(3):155-9.
